Figure 4.
Callus area in X-ray images of tibia fractures was measured and compared with the area of normal bone at the same site on the opposite leg of the mice. Four weeks after injury, the decreased bone area of the xylan/chitosan composite group reveals the desired remodeling of hard callus, indicating faster healing compared with the group treated with pure chitosan hydrogel. The control is the uninjured, contralateral bone. Each treatment group had five animals. The symbol “*” denotes a p-value ≤0.05, and the symbol “**” denotes a p-value ≤0.01.