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. 2016 Aug 8;126(9):3567–3579. doi: 10.1172/JCI87382

Figure 1. SBI-477 is a small-molecule inhibitor of neutral lipid accumulation in human skeletal myotubes.

Figure 1

(A) Chemical structure of SBI-477. (B) Effects of SBI-477, over a dose range, on triglyceride levels in human skeletal myotubes following a 24-hour exposure to 100 μM oleate. Data are shown as the percentage of DMSO vehicle control and are representative of more than 5 experiments. (C) Effects of SBI-477 on human skeletal myotube neutral lipid accumulation as visualized by AdipoRed staining (red). Cell nuclei were stained with DAPI (blue). Images shown are representative of more than 3 images.