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. 2016 Aug 8;126(9):3567–3579. doi: 10.1172/JCI87382

Figure 2. SBI-477 inhibits expansion of cellular DAG and TAG pools in oleate-loaded myocytes.

Figure 2

Results of quantitative lipidomic analyses performed on human skeletal myotubes exposed to BSA or 100 μM oleate in the presence of DMSO vehicle (white bars) or 10 μM SBI-477 (black bars) for 24 hours. (A) Total mean TAG and DAG levels are shown. (B) Levels of individual TAG fatty acyl species, with 18:1 species shown separately (left). Data represent the mean ± SD (n = 3). *P < 0.05 versus vehicle; †P < 0.05 versus oleate-loaded vehicle; Student’s t test.