Skip to main content
. 2016 Aug 15;126(9):3417–3432. doi: 10.1172/JCI85880

Figure 8. CAPN6 is localized in macrophages/foam cells in human moderate-to-severe atheromas.

Figure 8

(A) CAPN6 expression in macrophages in human normal aorta and severe coronary atheromas. (B) CAPN6 expression in macrophages in human aortic atheromas. Scale bars: 50 μm (A and B). (C) CAPN6 expression in CD68-positive cells was quantified with respect to each specimen. (D) Statistical comparison of CAPN6 expression in human macrophages/foam cells. Specimens were divided into 3 groups based on the atherosclerosis grade. CD68 served as a macrophage marker. Arrows represent CAPN6-positive macrophages. **P < 0.01; *P < 0.05, 1-way ANOVA followed by Bonferroni’s test (D).