Table 4.

Binding free energy (MM-PBSA) and their components (kJ/mol) of T7RNAP complex with heparin and its LMW versions.

ID	BINDING ENERGY	VAN DER WAAL ENERGY	ELECTROSTATIC ENERGY	POLAR SOLVATION ENERGY	SASA ENERGY
Heparin	−240.288 ± 33.119	−479.880 ± 14.535	−110.557 ± 26.446	392.004 ± 38.629	−41.855 ± 1.523
Enoxaparin	−51.917 ± 23.402	−241.341 ± 19.358	−64.980 ± 22.338	279.895 ± 44.239	−25.491 ± 2.479
Bemiparin	−12.759 ± 21.126	−124.041 ± 8.199	−5.431 ± 16.425	130.885 ± 28.575	−14.172 ± 1.172