Table 3.
Univariate and multivariate logistic regression analysis for LLNM in patients with PTMC
Independent variable | Univariate
|
Multivariate
|
||
---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |
Sex (female vs male) | 0.374 (0.337–0.415) | 0.001 | 0.360 (0.322–0.401) | 0.001 |
Age (≥45 vs <45 years) | 0.545 (0.493–0.601) | 0.001 | 0.503 (0.453–0.559) | 0.001 |
Race | ||||
Black | 1 (reference) | 1 (reference) | ||
White | 3.141 (2.239–4.407) | 0.001 | 2.441 (1.730–3.443) | 0.001 |
Othera | 3.851 (1.971–5.868) | 0.001 | 2.620 (1.802–3.808) | 0.001 |
Size | 1.170 (1.150–1.191) | 0.001 | 1.112 (1.091–1.133) | 0.001 |
Histology (PTMC vs FV-PTMC) | 0.591 (0.521–0.670) | 0.001 | 0.625 (0.549–0.711) | 0.001 |
Multifocality | 2.845 (2.575–3.145) | 0.001 | 2.265 (2.039–2.517) | 0.001 |
ETE | ||||
Negative | 1 (reference) | 1 (reference) | ||
Capsule | 2.405 (1.934–2.992) | 0.001 | 2.105 (1.681–2.637) | 0.001 |
Minimal | 6.042 (5.295–6.895) | 0.001 | 4.601 (3.994–5.300) | 0.001 |
Gross | 9.909 (7.048–13.931) | 0.001 | 7.093 (4.910–10.246) | 0.001 |
Metastasisb | 17.880 (11.846–26.987) | 0.001 | 11.948 (7.523–18.975) | 0.001 |
Notes:
Including American Indian/Alaska Native and Asian/Pacific Islander.
Including the lungs, bones, and brains.
Abbreviations: LLNM, lateral lymph node metastasis; PTMC, papillary thyroid microcarcinoma; OR, odds ratio; CI, confidence interval; FV-PTMC, follicular variant of papillary thyroid microcarcinoma; ETE, extrathyroidal extension.