Table 5.

The results of multifactor logistic regression analysis

Factor	Odds ratio	95% CI	P-value*
CA-SSR1	2.74	1.31–5.85	0.017
-216G/T	4.29	2.62–6.46	0.021
R497K	1.72	1.03–2.86	0.039

Notes: Based on a Cox proportional hazards model; adjusted by smoking, age, sex, and tumor differentiation degree. The results of multifactor logistic regression analysis suggested that the factors including smoking, age, sex, and tumor differentiation degree were not closely associated with pleural metastasis (*P>0.05), while the CA-SSR1, -216G/T and R497K polymorphisms concerned the risk of the pleural metastasis of lung adenocarcinoma (*P<0.05).

Abbreviations: CA-SSR1, CA simple sequence repeat in intron 1; 95% CI, 95% confidence interval.