Table 2. Stifle radiographic parameters before and after injection with bone marrow-derived mesenchymal stem cells.
Radiographic parameter | Partial CR stifle | Complete CR stifle | ||
---|---|---|---|---|
Diagnosis | 8 weeks | Diagnosis | 8 weeks | |
Synovial effusion severity score | 1.5 (1, 2) | 2 (1, 2) | 2 (2, 2)a | 2 (1, 2) |
Osteophytosis severity score | 1 (1, 3) | 1 (1, 3) | 2 (1, 3)b | 2 (2, 3) |
CrCLd (mm) | 33.5±2.9 | 32.1±3.3 | 38.9±2.9c | 33.7±2.4d |
Note: Instability in the complete CR stifle was treated with tibial plateau leveling osteotomy at diagnosis. CrCLd represents the functional length of the ligament under load as determined by weight-bearing radiography [28].
aP<0.05
bP<0.01
cP<0.005 versus contralateral stifle.
dP = 0.06 versus complete CR stifle at diagnosis. Abbreviations: CR, cruciate ligament rupture; CrCL, cranial cruciate ligament.