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. 2016 Sep;138(3):e20153036. doi: 10.1542/peds.2015-3036

TABLE 5.

Performance of M-CHAT and M-CHAT/F Screens Predicting ASD or Suspected ASD Diagnosis

Variable Na Ratio (95% CI) z Test, P TOST
z1 P z2 P
PPVb .001 .94 <.001
 M-CHAT 98 0.57 (0.47–0.67)
 PCP M-CHAT/F 98 0.78 (0.69–0.86)
PPVc .30 .29 .004
 PCP M-CHAT/F 98 0.78 (0.69–0.86)
 AC M-CHAT/F 97 0.71 (0.62–0.80)
Sensitivityc .38 0.30 .01
 PCP M-CHAT/F 98 0.55 (0.46–0.65)
 AC M-CHAT/F 97 0.49 (0.39–0.59)
Specificityc .43 .20 .008
 PCP M-CHAT/F 98 0.79 (0.70–0.87)
 AC M-CHAT/F 97 0.74 (0.65–0.83)
Accuracyc .24 .40 .005
 PCP M-CHAT/F 98 0.60 (0.56–0.75)
 AC M-CHAT/F 97 0.57 (0.47–0.67)

Table includes suspected ASD/new phenotype. Comparisons were made with 2-tailed z test and TOST, Δ = 0.1 unit of proportion. Only patients with a positive screen on the M-CHAT are included in this sample. CI, confidence interval.

a

One patient did not have a complete AC M-CHAT/F (Fig 1).

b

Relevant difference.

c

Equivalence.