TABLE 3.
Receiver operating characteristic analysis assessing the prognostic accuracy of N-terminal pro-brain natriuretic peptide (NT-proBNP), pro-atrial natriuretic peptide (proANP), high-sensitivity troponin T (hsTnT), soluble fms-like tyrosine kinase 1 (sFlt-1), growth differentiation factor 15 (GDF-15) and placental growth factor (PlGF) for prediction of 4-year mortality
| NT-proBNP | ProANP | hsTnT | sFlt-1 | GDF-15 | PlGF | |
| AUC | 0.789 | 0.822 | 0.782 | 0.733 | 0.728 | 0.580 |
| p-value | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.0001 | 0.2066 |
| J (95% CI) | 0.5278 (0.3214–0.6830) | 0.4978 (0.3589–0.6347) | 0.4978 (0.3087–0.6378) | 0.4842 (0.2765–0.6242) | 0.4319 (0.2021–0.5800) | 0.4978 (0.1100–0.3442) |
| Cut-off value ng·L−1 (95% CI) | >704.52 (>251.46– >1142.51) | >77 427.3 (>37 793.36– >100 881.76) | >16.13 (>3– >18.37) | >75.9 (>73.25– >119.09) | >1759.2 (>741.6– >1955.99) | >17.15 (>13.59– >26.21) |
| Sensitivity % | 77.78 | 70.37 | 70.37 | 85.19 | 74.07 | 66.67 |
| Specificity % | 75.00 | 79.41 | 79.41 | 63.24 | 69.12 | 55.88 |
AUC: area under the curve; J: Youden index.