TABLE 1.
Healthy | Cystic fibrosis | p-value | |
Subjects | 15 | 15 | |
Male | 13 (87) | 12 (80) | |
Age years | 25±3 | 24±5.5 | 0.620 |
Height cm | 1.78±0.09 | 1.70±0.08 | 0.020 |
Weight kg | 76.7±9.5 | 60.9±9.1 | 0.001 |
BMI kg·m−2 | 23.9±1.4 | 20.9±2 | 0.002 |
FEV1 % pred | 107±12 | 53.5±24 | 0.001 |
VC % pred | 104±13 | 65.9±23 | 0.001 |
FEV1/VC | 99±11 | 64±64 | 0.001 |
PEF L·min−1 | 369±109 | ||
TLC % pred | 105±33 | ||
RV % pred | 191±38 | ||
PaO2 kPa | 10.7±1.5 | ||
PaCO2 kPa | 5.1±0.75 | ||
HCO3− mmol·L−1 | 24.7±3.4 | ||
pH | 7.42±0.01 | ||
SaO2% | 99±1 | 96.±1 | 0.001 |
Data are presented as n, n (%) or mean±sd, unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; % pred: % predicted; VC: vital capacity; PEF: peak expiratory flow; TLC: total lung capacity; RV: residual volume; PaO2: arterial oxygen tension; PaCO2: arterial carbon dioxide tension; HCO3−: bicarbonate; SaO2: arterial oxygen saturation.