TABLE 3.

Sensitivity analysis

Study and year of publication	Weight	SMD (95% CI)	I2	p-value
Dubiley and Shogentsukova, 1973 [18] (three groups combined)	12.53	0.35 (0.25–0.46)	64	<0.001
Kolesaret al., 1977 [19]	1.77	0.53 (0.43–0.63)	85	<0.001
Boneret al., 1985 [20]	1.41	0.52 (0.42–0.62)	85	<0.001
Bobokhodzhaev and Shirinskii, 1990 [21] (two groups combined)	4.75	0.51 (0.41–0.61)	86	<0.001
Brimkulov, 1991 (2) [22] (two groups combined)	14.19	0.48 (0.38–0.59)	84	<0.001
Piacentiniet al., 1993 [23]	2.40	0.54 (0.44–0.64)	85	<0.001
Simonet al., 1994 [24]	1.59	0.53 (0.43–0.62)	85	<0.001
Allegraet al., 1995 [11]	1.32	0.53 (0.44–0.63)	85	<0.001
Boneret al., 1995 [25] (two groups combined)	2.23	0.53 (0.43–0.62)	86	<0.001
van Velzenet al., 1996 [12]	1.91	0.53 (0.44–0.63)	85	<0.001
Kokov, 1996 [26]	8.06	0.55 (0.45–0.65)	85	<0.001
Vallettaet al., 1997 [27]	1.67	0.53 (0.44–0.63)	85	<0.001
Grootendorstet al., 2001 [28]	2.09	0.53 (0.43–0.63)	85	<0.001
Peroniet al., 2002 [29]	2.16	0.54 (0.44–0.64)	85	<0.001
Straubet al., 2004 [30]	5.76	0.55 (0.46–0.65)	85	<0.001
Louie and Pare, 2004 [31]	0.40	0.54 (0.44–0.63)	85	<0.001
Peroniet al., 2009 [32]	2.64	0.54 (0.44–0.64)	85	<0.001
Huismanset al., 2010 [33]	2.83	0.56 (0.46–0.65)	84	<0.001
Rijssenbeek-Nouwenset al., 2012 [34] (two groups combined)	16.32	0.58 (0.47–0.68)	85	<0.001
Seyset al., 2013 [35]	2.07	0.53 (0.43–0.62)	85	<0.001
Verkleijet al., 2013 [14] (two groups combined)	11.90	0.60 (0.49–0.70)	85	<0.001

Data are presented as % or n unless otherwise stated. SMD: standardised mean difference.