TABLE 3.
Comorbidity in asthma patients with low (<0.3×109 L−1) versus high (≥0.3×109 L−1) blood eosinophil counts
| Total group | Blood eosinophils <0.3×109 L−1 | Blood eosinophils ≥0.3×109 L−1 | p-value | |
| Patients | 491 | 361 | 130 | |
| IgE kU·L−1 | 59 (19–206) | 41 (12–122) | 149 (56–289) | <0.001 |
| Atopy# | 30.5% | 30.2% | 31.5% | 0.775 |
| Fungal sensitivity¶ | 5.5% | 5.3% | 6.2% | 0.707 |
| NSAID intolerance | 8.8% | 8.3% | 10.0% | 0.559 |
| GORD | 36.9% | 36.8% | 36.9% | 0.987 |
| SNOT score | 28 (0–80) | 27 (0–80) | 32 (2–75) | 0.043 |
| Nasal endoscopy score | 4 (1–8) | 4 (1–8) | 5 (1–9) | 0.124 |
| Nasal polyps | 19.3% | 14.5% | 33.8% | <0.001 |
| Sinus CT score | 2 (0–7) | 1 (0–5) | 8 (4–12) | <0.001 |
Data are presented as median (interquartile range) unless otherwise stated. NSAID: nonsteroidal anti-inflammatory drugs; GORD: gastro-oesophageal reflux disease; SNOT: Sino-Nasal Outcome Test; CT: computed tomography. #: patients with positive specific IgE to at least one allergen; ¶: patients with specific IgE to fungi.