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Ezrin inhibitor NSC305787 shows no effect on ERK phosphorylation in two EGFR-null cell lines. (A) Western blot analysis of EGFR levels in H1944 and H520 cells. A549 cell line was used as a positive control. (B) Cells were serum starved for 24 hours and treated with 5 μM NSC305787 or DMSO for 30 minutes before EGF treatment for 5 minutes. (C) Cells were serum starved for 24 hours and treated with 5 μM NSC305787 or DMSO for 30 minutes before HGF treatment for 5 minutes.
