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. 2015 Jul 8;310(4):C293–C304. doi: 10.1152/ajpcell.00043.2015

Fig. 6.

Fig. 6.

CAIX downregulation abrogates PDGF-D-mediated extracellular acidosis. PDGF-D BPH-1 (A) or BPH-1 CAFTD-4 (D) cells were transfected with scrambled (shScrm) or two separate CAIX shRNA and its knockdown was monitored via immunoblotting. Changes in extracellular pH were monitored then normalized to cell number in control and shRNA-mediated CAIX knockdown PDGF-D BPH-1 (B and C) or BPH-1 CAFTD-4 (E and F). Bars represent the mean ± SD. *P < 0.05, between shScrm and shCAIX-2; **P < 0.05, between shScrm and shCAIX-3.