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. 2016 Jan 21;120(8):876–888. doi: 10.1152/japplphysiol.00727.2015

Fig. 2.

Fig. 2.

Phosphorylation of proinflammatory transcription factors is increased in LKB1-deficient muscles 0 and 2 h after in situ skeletal muscle contractions. Western blotting was performed using protein from WT and skeletal muscle-specific LKB1-knockout (skmLKB1-KO or KO) muscles immediately or 2 h after a 15-min in situ contraction bout. A: content of phosphorylated and total NF-κB and STAT-3 protein in gastrocnemius muscles immediately after a 15-min bout of electrically stimulated contractions. B: content of phosphorylated and total NF-κB and STAT-3 protein in gastrocnemius muscles 2 h after a 15-min bout of electrically stimulated contractions. Re, resting muscles; St, stimulated muscles. n = 8/group. *Significant difference (P ≤ 0.05) vs. corresponding REST group. #Significant difference vs. corresponding WT group. aMain effect of stimulation. bMain effect of genotype.