Table 2.
GO terms overrepresented in KO vs. WT muscles following contraction, ranked by P value
| Rank | ID | Term | Pl | n Genes |
|---|---|---|---|---|
| 1 | GO:0008152 | Metabolic process | 1.23E-07 | 132 |
| 2 | GO:0044710 | Single-organism metabolic process | 6.25E-07 | 69 |
| 3 | GO:0006950 | Response to stress | 8.80E-07 | 47 |
| 4 | GO:0044237 | Cellular metabolic process | 9.25E-07 | 115 |
| 5 | GO:0006979 | Response to oxidative stress | 1.11E-06 | 12 |
| 6 | GO:0009987 | Cellular process | 4.74E-06 | 167 |
| 7 | GO:0035556 | Intracellular signal transduction | 7.28E-06 | 37 |
| 8 | GO:0071704 | Organic substance metabolic process | 1.37E-05 | 116 |
| 9 | GO:0006793 | Phosphorus metabolic process | 1.39E-05 | 49 |
| 10 | GO:0055114 | Oxidation-reduction process | 1.93E-05 | 25 |
| 11 | GO:0016265 | Death | 2.16E-05 | 33 |
| 12 | GO:0010941 | Regulation of cell death | 2.34E-05 | 29 |
| 13 | GO:0051179 | Localization | 2.36E-05 | 71 |
| 14 | GO:0055013 | Cardiac muscle cell development | 2.41E-05 | 5 |
| 15 | GO:0016477 | Cell migration | 2.42E-05 | 21 |
| 16 | GO:0010940 | Positive regulation of necrotic cell death | 2.45E-05 | 2 |
| 17 | GO:0044699 | Single-organism process | 2.56E-05 | 154 |
| 18 | GO:0040011 | Locomotion | 3.03E-05 | 26 |
| 19 | GO:0055002 | Striated muscle cell development | 3.45E-05 | 8 |
| 20 | GO:0061061 | Muscle structure development | 3.51E-05 | 15 |
KO, skeletal muscle-specific liver kinase B1 (LKB1) knockout mice; WT, wild-type littermates.