Fig. 7.

XE991 decreases firing frequency. A: action potentials in a CZ calyx terminal under control conditions and after application of 20 μM XE991. Firing decreased from 37.7 Hz to 16.7 Hz. B: median frequency decreased from 15.3 Hz to 5.6 Hz (n = 6, 3 CZ and 3 PZ; *P < 0.05, Wilcoxon signed-rank test). C: XE991 increased spike half-width from a mean of 1.3 ms to 1.6 ms, decreased the size of the afterhyperpolarization potential, and delayed the onset of the next action potential. Each trace is the average of 3 evoked spikes (same cell as in A).