Table 1.
Zonal variations in calyx properties
| PZ | CZ | PPZ, CZ | |
|---|---|---|---|
| Mean CV | 0.36 ± 0.07 (n = 11) | 0.33 ± 0.05 (n = 9) | ns |
| Mean firing rate, spikes/s | 16.6 ± 4.0 (n = 19) | 17.4 ± 3.4 (n = 10) | ns |
| Median outward K+ current inactivation, % | 9.4 (n = 66) | 4.2 (n = 33) | <0.001 (Mann-Whitney) |
| Median peak K+ current amplitude, pA | 1,943 (n = 66) | 2,788 (n = 33) | <0.05 (Mann-Whitney) |
| Median peak Na+ current amplitude, pA | −1,303 (n = 66) | −1,618 (n = 33) | <0.05 (Mann-Whitney) |
| Whole cell capacitance, pF | 6.2 ± 0.7 (n = 13) | 8.1 ± 2.3 (n = 6) | ns |
| % Decrease in 20 μM XE991 | 31.4 ± 3.6 (n = 10) | 17.6 ± 3.3 (n = 8) | <0.05 (t-test) |
| % Increase in 100 μM diclofenac | 14.3 ± 5.8 (n = 6) | 23.3 ± 14 (n = 4) | ns |
| % Decrease in 10–50 μM 4-AP | 35 ± 4.2 (n = 7) | 21 ± 3.8 (n = 6) | <0.05 (t-test) |
| % Decrease in 100–250 nM α-DTX | 3.5 ± 0.1 (n = 6) | 12.8 ± 0.3 (n = 6) | <0.05 (t-test) |
Values are means ± SE. PZ, peripheral zone; CZ, central zone; CV, coefficient of variation; 4-AP, 4-aminopyridine; α-DTX, α-dendrotoxin; ns, not significant.