Fig. 4.

Blood pressure response to acute ANG II infusion following inhibition of the endogenous RAS at 12 and 18 mo of age. A: change in blood pressure in response to ANG II. B: MAP in male control and IUGR offspring at baseline and in response to acute infusion of ANG II (100 ng·kg⁻¹·min⁻¹) in conscious, chronically instrumented animals at 12 and 18 mo of age that were pretreated with the ACE inhibitor enalapril. 12-mo group: control n = 11, IUGR n = 12; 18-mo group: control n = 5, IUGR n = 6. *P < 0.05 vs. controls at baseline. †P < 0.05 vs. IUGR at baseline. All data are means ± SE.