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. 2016 May 27;311(2):H465–H475. doi: 10.1152/ajpheart.00899.2015

Table 2.

Mechanical parameters from trabeculae at MI20W and AMC20W

AMC20W at 32 μM (n = 12) MI20W at 32 μM (n = 8) AMC20W at 1 μM (n = 9) MI20W at 1 μM (n = 8)
F0, kN/m2 66 ± 6 62 ± 9 30 ± 3* 22 ± 3*
Vmax, ML/s 7.2 ± 0.6 4.8 ± 0.4 2.1 ± 0.2* 2.4 ± 0.8*
VPP, ML/s 1.2 ± 0.1 0.8 ± 0.1 0.7 ± 0.1* 0.7 ± 0.2*
PP, kW/m3 14 ± 6.8 7.5 ± 1.4 5.9 ± 0.5* 4.2 ± 0.6*
a/P0 0.05 ± 0.01 0.05 ± 0.08 0.39 ± 0.11* 0.32 ± 0.11*
FPP, kN/m2 12 ± 1.4 9.5 ± 1.4 9.4 ± 0.8* 6.3 ± 1.0*
FPP/F0 0.18 ± 0.01 0.16 ± 0.01 0.32 ± 0.01* 0.29 ± 0.02*
CSA, μm2 12600 ± 2250 10700 ± 2380 20600 ± 2590 32000 ± 4710

Values are means ± SE. Mechanical parameters for MI20W and ACM20W trabeculae are tabulated. F0, peak isometric force; Vmax, peak unloaded shortening velocity; VPP, velocity at which peak power is attained, PP is the peak power; a/Po, curvature of the hyperbolic fit of the force-velocity data; FPP is the force at peak power; FPP/Po; ratio of force at peak isometric force; CSA, cross-sectional area of the trabeculae; ML, muscle length.

*

P < 0.05, significant [Ca2+] effect.

P < 0.05, significant effect of myocardial infarction (MI).

P < 0.05, interaction effect between [Ca2+] and MI.