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ATM deficiency decreases GSK-3β activation 28 days post-MI. Total LV lysates, prepared from sham, noninfarct (Non), and infarct (Inf) regions post-MI, were analyzed by Western blot using phospho-specific GSK-3β (Ser-9) antibodies. Top: autoradiograms indicating immunostaining for p-GSK-3β and GAPDH. Bottom: quantitative analyses of p-GSK-3β normalized to GAPDH (*P < 0.05 vs. WT-Inf; n = 7).
