Table 3.

Subjective evaluation of change in temperature (°C)

Variable—visit	Femprox: subjective change		Placebo: subjective change
No (n = 1)	Yes (n = 9)	No (n = 7)	Yes (n = 3)
Predose genital sensation	3.0	2.6	1.9	2.3
Vestibule
Baseline temperature	35.4	34.6	34.4	34.9
Mean change over 61 min	0.44	0.58	−1.05	−1.00
Maximum temperature over 61 min	36.5	36.3	33.9	34.3
Time (min) of maximum temperature	43	48	33	34
Clitoris
Baseline temperature	35.1	34.5	34.1	34.5
Mean change over 61 min	0.30	0.53	−0.86	−0.83
Maximum temperature over 61 min	36.2	36.2	33.8	34.0
Time (min) of maximum temperature	43	49	32	32
Vulva
Baseline temperature	34.6	34.2	33.9	34.2
Mean change over 61 min	0.31	0.26	−0.91	−0.71
Maximum temperature over 61 min	35.6	35.1	33.5	33.7
Time (min) of maximum temperature	61	48	14	22