Appendix 1.

Subjective questionnaires

Predose
Initials:	Number:		Date:
Using the scale below, please rate your current genital sensations (eg, warmth in genitals, genital wetness or lubrication, tingling, or fullness).
1	2	3	4	5
Barely noticeable		Neutral		Intense
Postdose
Initials:	Number:		Date:
1. Did you notice any change in genital sensations (eg, warmth in genital, genital tingling or fullness) after applying the study medication?
☐ Yes	☐ No
a. If yes, how intense were those sensations (please circle the number)?
1	2	3	4	5
Barely noticeable		Neutral		Intense
b. If yes, how would you describe those sensations (please circle the number)?
1	2	3	4	5
Negative		Neutral		Positive
c. If yes, when were the sensations the most intense (please circle the number)?
1. Almost immediately after applying the medication
2. Within 5–10 minutes after applying the medication
3. More than 30 minutes after applying the medication
4. I couldn't tell
d. If yes, how long did the sensations last (please circle the number)?
1. Less than 5 minutes
2. Within 5–10 minutes
3. Longer than 30 minutes
4. I couldn't tell