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. 2016 Mar 13;4(2):e85–e90. doi: 10.1016/j.esxm.2016.01.002

Table 3.

Comparison among major series investigating intralesional therapies for Peyronie's disease

Levine et al,14 2002 Hellstrom et al,28 2006 Bennett et al,25 2007 Present study
Patients, n 156 117 94 65
Drug Verapamil Interferon alfa2b Verapamil Hyaluronic acid
Dose 10 mg every 2 wk 2 × 106 U biweekly 10 mg every 2 wk 8 mg/wk
Study design Prospective, non-randomized, single-arm study Single-blinded, multicenter, placebo-controlled, parallel-group study Prospective, non-randomized, single-arm study Prospective, non-randomized, single-arm, multicenter, pilot study
Injections, n 12 6 6 10
Decrease in penile curvature, % 60 27 18 37
Increased sexual satisfaction, % 71 Not available Monopoli Monopoli
Decrease in plaque size, % Not available 54.6 Not available 57