Table 3.
Comparison among major series investigating intralesional therapies for Peyronie's disease
| Levine et al,14 2002 | Hellstrom et al,28 2006 | Bennett et al,25 2007 | Present study | |
|---|---|---|---|---|
| Patients, n | 156 | 117 | 94 | 65 |
| Drug | Verapamil | Interferon alfa2b | Verapamil | Hyaluronic acid |
| Dose | 10 mg every 2 wk | 2 × 106 U biweekly | 10 mg every 2 wk | 8 mg/wk |
| Study design | Prospective, non-randomized, single-arm study | Single-blinded, multicenter, placebo-controlled, parallel-group study | Prospective, non-randomized, single-arm study | Prospective, non-randomized, single-arm, multicenter, pilot study |
| Injections, n | 12 | 6 | 6 | 10 |
| Decrease in penile curvature, % | 60 | 27 | 18 | 37 |
| Increased sexual satisfaction, % | 71 | Not available | Monopoli | Monopoli |
| Decrease in plaque size, % | Not available | 54.6 | Not available | 57 |