Table 10.

Skin hydration value changes

		BG11001	Placebo	p1)	p2)
Arbitrary units (Average ± SD)
Corneo-meter	Baseline	72.23 ± 10.20	70.90 ± 11.77	0.692
After 8 wk	67.79 ± 9.57	65.46 ± 9.67	0.222	0.083
Difference3)	−4.44 ± 8.46	−5.44 ± 8.54	0.149
p4)	0.058	0.485
After 16 wk	65.67 ± 10.34	63.43 ± 9.29	0.074	0.008**
Difference5)	−6.56 ± 8.65	−7.46 ± 11.68	0.036
p4)	0.282	0.071
After 24 wk	67.49 ± 10.49	63.89 ± 10.87	0.090	0.005**
Difference6)	−4.74 ± 9.19	−7.01 ± 12.96	0.005
p4)	0.172	0.013∗

^∗p < 0.05 by Student t-test for comparison with placebo group.

^∗∗p < 0.01 by Student t-test for comparison with placebo group.

¹⁾Compared between groups: p by Student t-test.

²⁾Compared between groups: p-value by analysis of covariance (adjustment with baseline).

³⁾After 8 wk – baseline.

⁴⁾Compared within groups: p-value by paired t-test.

⁵⁾After 16 wk – baseline.

⁶⁾After 24 wk – baseline.