Table 11.

Transepidermal water loss value changes

		BG11001	Placebo	p1)	p2)
Arbitrary units (Average ± SD)
Tewa-meter	Baseline	14.29 ± 2.60	14.94 ± 3.25	0.332
After 8 wk	13.67 ± 2.47	15.16 ± 3.98	0.051	0.062
Difference3)	−0.62 ± 1.79	0.22 ± 2.47	0.091
p4)	0.039	0.580
After 16 wk	13.68 ± 2.62	14.96 ± 3.73	0.083	0.109
Difference5)	−0.61 ± 0.96	0.02 ± 2.56	0.154
p4)	0.000∗∗	0.958
After 24 wk	13.75 ± 2.92	15.30 ± 3.12	0.027	0.030*
Difference6)	−0.53 ± 1.81	0.36 ± 2.57	0.081
p4)	0.073	0.391

^∗p < 0.05 by Student t-test for comparison with placebo group.

^∗∗p < 0.01 by Student t-test for comparison with placebo group.

¹⁾Compared between groups: p by Student t-test.

²⁾Compared between groups: p-value by analysis of covariance (adjustment with baseline).

³⁾After 8 wk – baseline.

⁴⁾Compared within groups: p-value by paired t-test.

⁵⁾After 16 wk – baseline.

⁶⁾After 24 wk – baseline.