Fig. 1.
Anticancer effect of joboksansam powder in a xenograft mouse bearing RMA cell-derived cancer. Mice were injected with RMA cells (1 × 106 cells per mouse) subcutaneously into the back next to the right hind leg. Mice were then sorted into two groups (n = 14/group) and orally administered joboksansam (400 mg/kg) or vehicle. (A) Tumor size was measured on the indicated days until the experimental endpoint. (B) Weight of mice was measured on each indicated day. (C) Photographs of xenograft mice bearing RMA cell-derived cancer. (D) The cancer tissues were measured (left panel) and photographed (right panel) at 33 d. (E) Mortality of mice was determined on the indicated days. *p < 0.05, **p < 0.01 compared with control.