Figure 1.

Patterns of cerebral hemodynamic changes during periodic limb movement with arousal (PLMA) in each patient with PLMS. A time window including several PLMA events is chosen to better illustrate the hemodynamic patterns. Subfigures (A–D) present results from Patient No. 1–4, respectively. PLMA events induce periodic changes in HbO₂, HHb, and blood volume (BV), as shown in the panel of each subfigure. The hemodynamic changes are expressed in arbitrary units (A.U.), as the mean value of 10-s baseline measurements before the onset of the first event of the selected data fragment is set at 0.