Figure 2.

Difference between the Imputed Marginal Statistics and Analytical Marginal Statistics for TG Phenotype

Imputed marginal statistics are obtained from the association between the genotype and the imputed phenotype. Analytical marginal statistics are equal to the marginal statistics computed on the true target phenotype scaled by r_imp. The blue curve is the normal distribution with a mean of 0 and a variance of 1 − $r_{imp}^2$. This histogram indicates that the difference follows a normal distribution (mean 0 and variance 1 − $r_{imp}^2$). Thus, for most null variants the NMM assumption holds.