Table 3.
Variants Associated with Both PLT and MPV
| rsID | Gene | PLT | MPV |
|---|---|---|---|
| rs12566888 | PEAR1 | ↑ | ↓ |
| rs1668873 | TMCC2 | ↑ | ↓ |
| rs56043070 | GCSAML | ↓ | ↑ |
| rs12485738 | ARHGEF3 | ↑ | ↓ |
| rs56106611 | KALRN | ↑ | ↓ |
| rs34592828 | IQGAP2 | ↓ | ↑ |
| rs1012899 | LRRC16A | ↓ | ↑ |
| rs342293 | PIK3CG | ↓ | ↑ |
| rs2343596 | ZFPM2 | ↓ | ↑ |
| rs10761731 | JMJD1C | ↑ | ↓ |
| rs11602954 | BET1L | ↑ | ↓ |
| rs10506328 | NFE2 | ↑ | ↓ |
| rs2958154 | PTGES3 | ↓ | ↑ |
| rs7961894 | WDR66 | ↓ | ↑ |
| rs1465788 | ZFP36L1 | ↑ | ↓ |
| rs2297067 | EXOC3L4 | ↑ | ↓ |
| rs2138852 | TAOK1 | ↓ | ↑ |
| rs10512472 | SLFN14 | ↑ | ↓ |
| rs11082304 | CABLES1 | ↓ | ↑ |
| rs6136489∗ | SIRPA/LOC727993 | ↓ | ↓ |
| rs41303899 | TUBB1 | ↓ | ↑ |
| rs6070697 | TUBB1 | ↑ | ↓ |
| rs1018448 | ARFGAP3 | ↓ | ↑ |
All variants listed here showed association with both PLT and MPV in the opposite direction of effect as indicated by the arrows, except for rs6136489 (denoted by asterisk), which showed association with decreased PLT and decreased MPV. Abbreviations are as follows: PLT, platelet count; MPV, mean platelet volume.