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. 2016 Jun 3;48(8):565–572. doi: 10.1152/physiolgenomics.00125.2015

Fig. 1.

Fig. 1.

Predisposing risk factors and maternal/fetal outcomes of preeclampsia (PE). The pregnancy-specific disorder PE occurs spontaneously and without warning. Maternal conditions pre-existing before pregnancy are thought to significantly increase the risk of developing PE; however, the incidence is still unpredictable. Signs of PE resolve upon delivery of the placenta; therefore, it is considered the causative organ. This dysregulated placenta masterminds its potent effects on the fetus and mother during pregnancy but can also leave lasting detrimental effects on the health of both mother and offspring.