Table III.
Gene ontology enrichment analysis results of identified gene modules
| Gene ontologyname | Gene ontology number | Enrichment score* | p-value | False discovery rate | |
|---|---|---|---|---|---|
| Synovium | Antigen processing and presentation of peptide antigen via MHC class I | 0002474 | 244.85 | 3.60E−07 | 4.86E-04 |
| Antigen processing and presentation of peptide antigen | 0048002 | 148.66 | 1.73E−06 | 2.33E-03 | |
| Eukaryotic translation initiation factor 4F complex | 0016281 | 355.06 | 2.42E−05 | 2.52E-02 | |
| Peripheral blood | Transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 21.96 | 2.97E−08 | 4.34E-05 |
| MHC class II protein complex | GO:0042613 | 97.95 | 6.99E−06 | 7.87E-03 | |
| Plasma membrane part | GO:0044459 | 3.87 | 1.74E−05 | 1.95E-02 | |
| Protein kinase cascade | GO:0007243 | 11.63 | 1.54E−05 | 2.25E-02 | |
| Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | GO:0002504 | 74.53 | 1.71E−05 | 2.50E-02 | |
| Positive regulation of kinase activity | GO:0033674 | 15.97 | 2.26E−05 | 3.31E-02 | |
| Positive regulation of transferase activity | GO:0051347 | 15.37 | 2.72E−05 | 3.98E-02 |
*
Enrichment score calculated by the DAVID tool
MHC, major histocompatibility complex