Table 1.

Genes responding differently to oAβ in SH versus EE mice at 24 and 48 h that belong to either cytokine signaling pathways or the JNK signaling pathway^a

Gene	Response to oAβ (7PA2:CHO− mRNA ratio)
	SH 24 h	SH 48 h	EE 24 h	EE 48 h	p(SH vs EE) 24 h	p(SH vs EE) 48 h
Ccl2	1.32 ± 0.04	—	1.00 ± 0.04	—	<0.001	—
Ccl3b	1.21 ± 0.03	1.73 ± 0.14	0.94 ± 0.03	0.89 ± 0.01	<0.001	<0.001
Ccl4b	1.29 ± 0.01*	1.68 ± 0.22	0.90 ± 0.03	1.02 ± 0.13	<0.0001	<0.05
Csf1	—	1.25 ± 0.08	—	0.82 ± 0.04	—	<0.01
IL-1β	—	1.58 ± 0.31	—	0.92 ± 0.22	—	<0.05
IL-6	1.65 ± 0.11	—	0.70 ± 0.17	—	<0.01	—
Mef2a	1.20 ± 0.07	—	0.86 ± 0.08	—	<0.01	—
Ptger3	—	0.74 ± 0.07	—	1.12 ± 0.04	—	<0.01
Rhoa	1.07 ± 0.02	—	1.01 ± 0.01	—	—	<0.05
Tgfb1	—	0.85 ± 0.05	—	1.02 ± 0.05	—	<0.05
Tnfb	1.20 ± 0.05	1.25 ± 0.02*	0.86 ± 0.00	0.94 ± 0.08	<0.001	<0.01
Fos	—	1.40 ± 0.12	—	1.18 ± 0.05	—	<0.05
Jun	1.12 ± 0.03	1.15 ± 0.10	0.97 ± 0.02	1.29 ± 0.02**	<0.01	—
Myc	1.43 ± 0.11	—	0.87 ± 0.02**	—	<0.001	—

^aAll genes in table are selected based on significant response to oAβ in SH mice without correction.

^bGene selected for further analysis.

*Significance with correction.

**Significance without correction.