Table 3.
The Cox proportional hazards model univariate survival analysis for functional and biochemical measures (hazard ratio of death per unit of measure)
| Measure | Hazard ratio | 95 % confidence interval | P value |
|---|---|---|---|
| MMSE, pointsa | 0.934 | 0.896–0.975 | .002 |
| Katz ADL, pointsa | 0.840 | 0.716–0.985 | .032 |
| Barthel Index, pointsa | 0.988 | 0.977–0.999 | .026 |
| Albumin, g/Lb | 0.926 | 0.870–0.986 | .016 |
| White blood cells, G/Lb | 1.161 | 1.059–1.273 | .001 |
| C-reactive protein, mg/Lb | 1.032 | 1.014–1.050 | <.001 |
| TNF-αc | 1.024 | 0.960–1.091 | .473 |
| IL-6, pg/mLc | 1.182 | 1.047–1.335 | .007 |
| ET-1, pg/mLc | 3.711 | 1.233–11.169 | .020 |
aAnalysis of 86 centenarians, among them 52 survivors and 34 non-survivors
bAnalysis of 84 centenarians, among them 52 survivors and 32 non-survivors
cAnalysis of 43 centenarians, among them 28 survivors and 15 non-survivors