Table 2.

Multivariable regressions per 1 SD decrement in muscle attenuation

Outcomea	Modelb	Women		Men		Overall
		(95 % CI)	p value	(95 % CI)	p value	(95 % CI)	p value
Mobility disability, OR	MV	1.25 (0.99, 1.58)	0.06	1.03 (0.77, 1.37)	0.86	1.15 (0.97, 1.37)	0.11
	MV + BMI	1.15 (0.90, 1.47)	0.25	1.02 (0.75, 1.38)	0.91	1.07 (0.89, 1.29)	0.47
	MV + VAT volume	1.07 (0.83, 1.39)	0.61	1.04 (0.77, 1.40)	0.81	1.08 (0.89, 1.30)	0.43
	MV + SAT volume	1.20 (0.94,1.53)	0.14	1.02 (0.76,1.38)	0.88	1.11 (0.93,1.33)	0.24
	Sex interaction						0.23
Grip strength, kg	MV	−0.07 (−0.49, 0.36)	0.76	−1.29 (−2.01, −0.57)	0.0005	−0.66 (−1.07, 0.25)	0.002
	MV + BMI	−0.10 (−0.54, 0.34)	0.66	−1.41 (−2.17, −0.65)	0.0003	−0.72 (−1.14, −0.30)	0.0009
	MV + VAT volume	−0.06 (−0.53, 0.40)	0.78	−1.38 (−2.13, −0.62)	0.0004	−0.07 (−1.13, −0.27)	0.002
	MV + SAT volume	−0.08 (−0.51,0.36)	0.74	−1.25 (−2.00, −0.50)	0.0012	−0.65 (−1.07, −0.23)	0.0023
	Sex Interaction						<0.0001
Walking speedc, m/s	MV	−0.04 (−0.06, −0.02)	<0.0001	−0.03 (−0.05, −0.01)	0.01	−0.03 (−0.05, −0.02)	<0.0001
	MV + BMI	−0.03 (−0.05, −0.01)	0.001	−0.02 (−0.04, 0.01)	0.14	−0.03 (−0.04, −0.01)	0.0008
	MV + VAT volume	−0.03 (−0.05, −0.01)	0.007	−0.02 (−0.05, 0.00)	0.077	−0.03 (−0.04, −0.01)	0.001
	MV + SAT volume	−0.03 (−0.05, −0.01)	0.0006	−0.02 (−0.04, 0.01)	0.13	−0.03 (−0.04, −0.01)	0.0005
	Sex interaction						0.06
Walking speed ≤1 m/sc, OR	MV	1.25 (1.02, 1.53)	0.03	1.35 (1.07, 1.71)	0.01	1.29 (1.11, 1.50)	0.0009
	MV + BMI	1.19 (0.97, 1.46)	0.096	1.29 (1.01, 1.64)	0.04	1.22 (1.05, 1.43)	0.009
	MV + VAT volume	1.15 (0.92, 1.43)	0.22	1.30 (1.02, 1.65)	0.03	1.21 (1.03, 1.42)	0.02
	MV + SAT volume	1.21 (0.99, 1.49)	0.07	1.31 (1.03, 1.67)	0.03	1.24 (1.07, 1.45)	0.004
	Sex interaction						0.86

OR odds ratio

^aOutcomes modeled per 1 standard deviation (7 unit decrement) in muscle attenuation (more intramuscular fat)

^bMV Model adjusts for age, current smoking status, diabetes, CVD, and physical activity score

^cWalking speed additionally adjusted for height