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. 2016 May 17;38(3):57. doi: 10.1007/s11357-016-9921-2

Table 2.

Effects of age and sex on mechanical and neural factors

Young Older Main effect Interaction effect
Age Sex
Male  (n = 11) Female (n = 13) Male (n = 11) Female (n = 9) Diff %, p value Diff %, p value Age × sex
p value
Muscle Strength and RTD KE MVIC (Nm) 317.9 ± 73.3 179.6 ± 52.2 167.2 ± 38.7 124.7 ± 31.8 39.1, <0.001 35.2, <0.001 <0.01
KF MVIC (Nm) 176.0 ± 53.0 96.0 ± 28.0 82.6 ± 20.9 55.1 ± 11.1 47.1, <0.001 38.7, <0.001 <0.05
RTD (Nm/s) 1044.7 ± 252.0 592.6 ± 185.5 413.2 ± 190.0 391.1 ± 136.3 49.6, <0.001 30.1, <0.001 <0.01
Tissue stiffness MAS (N/m) 1281.7 ± 403.4 796.4 ± 609.4 605.2 ± 213.8 485.5 ± 144.3 45.9, <0.001 29.1, <0.05 0.150
MS (N/m) 488.7 ± 50.2 416.7 ± 52.4 466.6 ± 39.7 394.2 ± 37.4 3.5, 0.115 14.7, <0.001 0.989
MA of VL Muscle thickness (mm) 24.6 ± 3.4 21.6 ± 2.7 20.3 ± 2.1 18.6 ± 1.5 15.1, <0.001 9.1, <0.01 0.397
Lf (mm) 105.1 ± 10.8 104.2 ± 7.1 88.1 ± 10.1 91.9 ± 11.1 14.1, <0.001 −2.6, 0.683 0.533
Ɵ (°) 13.5 ± 2.9 11.8 ± 1.9 13.1 ± 1.7 11.1 ± 1.4 3.0, 0.392 13.7, <0.01 0.847
Surface EMG VL activation (mV) 0.214 ± 0.063 0.160 ± 0.049 0.158 ± 0.073 0.119 ± 0.063 24.1, <0.05 22.8, <0.05 0.677
BF co-activation (%) 18.0 ± 10.2 25.9 ± 9.4 16.2 ± 10.7 20.4 ± 8.5 19.0, 0.223 −38.3, < 0.05 0.567
MDF (Hz) 65.6 ± 10.3 62.4 ± 9.0 58.6 ± 10.9 54.1 ± 7.2 11.4, <0.05 5.0, 0.193 0.815

Values are mean ± SD

KE knee extensors, KF knee flexors, MVIC maximal voluntary isometric contraction, RTD rate of torque development, MAS musculo-articular stiffness, MS muscle stiffness, MA muscle architecture, Lf fascicle length, Ɵ pennation angle, VL vastus lateralis, BF biceps femoris, MDF median frequency