Table 1.
VCI (n = 53) | CON (n = 23) | p value | |
---|---|---|---|
Gender, male/female | 40/13 | 16/7 | 0.59 |
Age (years) | 69.71 ± 9.01 | 67.61 ± 9.04 | 0.54 |
Education (years) | 9.41 ± 4.07 | 11.00 ± 2.88 | 0.30 |
MMSE | 25.90 ± 3.09 | 28.00 ± 1.23 | 0.005 |
MoCA | 19.47 ± 6.41 | 25.05 ± 3.85 | 0.004 |
z-score | −1.37 ± 1.35 | 0.23 ± 0.56 | <0.001 |
Total brain volume/ICV | 0.63 ± 0.05 | 0.65 ± 0.03 | 0.50 |
tAREMC scale score | 12 (7–22) | 8 (1–18) | <0.001 |
Fazekas PV score | 2.32 (1–3) | 1.50 (0–3) | 0.004 |
Fazekas DS score | 2.19 (1–3) | 1.75 (1–3) | 0.052 |
Microbleeds, % present | 37/53 | 8/23 | 0.004 |
Microbleeds, number | 8 (0–57) | 0 (0–22) | 0.005 |
SVCI, subcortical vascular cognitive impairment; CON, control group; MoCA, Montreal Cognitive Assessment, MMSE, Mini Mental State Examination; tARWMC, total Age-Related White Matter Changes, PV, periventricular; DS, deep subcortical. Note: all data were given as mean ± SD, except tARWMC and Fazekas score, i.e., data are given as median (range). Two-sample t-tests were performed to assess group comparisons. Mann–Whitney U test was used to compare continuous variables if data was not normally distributed. p-value < 0.05 was considered to be statistically significant.