Table 2.
Some of the meta-clusters characteristic of AML for the 23 AML samples in the training set.
Tube | Marker expression | #Samples | Fraction of cells |
---|---|---|---|
2 | KappalowLambdalowCD19+CD20− | 5 | 63% (±6.8) |
3 | CD7+CD4−CD8−CD2− | 4 | 18.0% (±4.8) |
4 | CD15−CD13+CD16−CD56− | 17 | 16.6% (±6.9) |
4 | CD15−CD13+CD16−CD56+ | 8 | 11.1% (±5.7) |
5 | CD14−CD11c−CD64−CD33+ | 10 | 13.5% (±5.2) |
5 | CD14−CD11c+CD64−CD33+ | 18 | 10.8% (±3.8) |
5 | CD14lowCD11c+CD64lowCD33+ | 6 | 13.8% (±4.3) |
6 | HLA-DR+CD117+CD34+CD38+ | 11 | 13.3% (±2.6) |
6 | HLA-DR+CD117±CD34+CD38+ | 13 | 17.3% (±6.6) |
6 | HLA-DR−CD117±CD34−CD38+ | 5 | 12.9% (±4.7) |
7 | CD5−CD19+CD3−CD10− | 3 | 12.3% (±2.4) |
7 | CD5+CD19−CD3−CD10− | 3 | 10.0% (±8.5) |
7 | CD5−CD19−CD3−CD10+ | 1 | 9.9% |
In the second column, “−,” “low,” and “+” denote very low, low, and high, abundance of a marker, respectively, and ± denotes a marker that is positively expressed by some samples and negatively expressed by others. The number of samples participating in a meta-cluster is shown in the third column. The average fraction of cells in a sample participating in a meta-cluster and the SD are shown in the fourth column.