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. 2016 May 24;45(3):806–815. doi: 10.1093/ije/dyw052

Table 3.

Associations between hydrogen sulphide (H 2 S, in quartiles and continuous) and cardiorespiratory morbidity: number of people hospitalized (No.), hazard ratios (HR) and 95% confidence intervals (95% CI)

Diagnosis (ICD-9-CM) H 2 S concentrations
<25° percentile a 25°–50° percentile
50°–75° percentile
>75° percentile
Linear trend
No. No. Crude HR HR 95% CI No. Crude HR HR 95% CI No. Crude HR HR 95% CI HR 95% CI
Total cohort
Cardiovascular diseases (390–459) 6 666 6 090 0.99 0.99 (0.95–1.03) 6 291 0.99 1.00 (0.96–1.04) 6 677 1.03 1.02 (0.97–1.07) 1.00 (0.99–1.02)
 Cardiac diseases (390–429) 3 991 3 585 0.99 0.98 (0.93–1.03) 3 580 0.97 0.98 (0.92–1.04) 4 022 1.05 1.04 (0.97–1.11) 1.01 (0.98–1.03)
 Ischaemic heart diseases (410–414) 1 393 1 347 1.03 1.02 (0.94–1.10) 1 288 0.94 0.94 (0.85–1.03) 1 426 1.01 0.99 (0.88–1.10) 0.99 (0.95–1.02)
 Cerebrovascular diseases (430–438) 1 635 1 482 0.98 0.98 (0.91–1.06) 1 466 0.97 0.97 (0.89–1.06) 1 543 0.97 0.98 (0.88–1.10) 0.99 (0.96–1.03)
Respiratory diseases (460–519) 4 372 4 249 0.98 0.97 (0.92–1.01) 5 628 1.02 1.01 (0.96–1.06) 4 837 1.06 1.05 (0.99–1.11) 1.02 (1.00–1.03)
 Acute respiratory infections (460–466,480–487) 1 447 1 441 1.00 0.96 (0.89–1.04) 1 721 1.00 0.97 (0.89–1.05) 1 509 1.09 1.07 (0.97–1.18) 1.02 (0.98–1.05)
 COPD (490–492;494;496) 654 592 0.96 0.94 (0.84–1.06) 535 0.92 0.90 (0.78–1.04) 577 1.09 1.06 (0.90–1.25) 1.00 (0.95–1.05)
 Asthma (493) 332 355 1.01 1.00 (0.86–1.17) 594 1.16 1.17 (0.99–1.38) 365 1.11 1.09 (0.90–1.33) 1.04 (0.98–1.11)
Children 014 years old
Respiratory diseases (460–519) 1 457 1 522 1.00 0.99 (0.92–1.07) 2 420 1.07 1.08 (0.99–1.17) 1 499 1.10 1.11 (1.01–1.22) 1.04 (1.01–1.07)
 Acute respiratory infections (460–466,480–487) 573 669 1.10 1.02 (0.91–1.15) 925 1.15 1.10 (0.97–1.25) 617 1.25 1.20 (1.04–1.38) 1.06 (1.02–1.11)
Asthma (493) 257 267 0.98 0.99 (0.83–1.19) 506 1.23 1.29 (1.06–1.55) 276 1.11 1.13 (0.91–1.41) 1.07 (0.99–1.14)

a Reference category