Table 2.
Significant clusters of activation in young adults.
| Region | L/R/B | X | Y | Z | t-value | Cluster size |
|---|---|---|---|---|---|---|
| Average | ||||||
| PumpsAverage > ControlAverage | ||||||
| Insula | R | 39 | 18 | 3 | 10.28 | 109 |
| Insula | L | -33 | 21 | 3 | 8.66 | 142 |
| Superior frontal gyrus | R | 30 | 57 | 15 | 7.12 | 143 |
| Middle frontal gyrus | L | -33 | 54 | 9 | 5.05 | 92 |
| Cingulate | B | 9 | 27 | 30 | 9.94 | 181 |
| Calcarine | R | 18 | -96 | -3 | 6.82 | 55 |
| Middle occipital gyrus | L | -18 | -96 | -3 | 7.06 | 67 |
| ControlAverage > PumpsAverage | ||||||
| Temporal lobe, Parietal lobe, Precuneus | B | 21 | -78 | 39 | 11.40 | 15251 |
| vmPFC | B | 36 | 42 | -18 | 7.27 | 478 |
| Parametric | ||||||
| PumpsParametric > ControlParametric | ||||||
| Insula | R | 39 | 21 | 6 | 6.08 | 73 |
| Insula | L | -39 | 15 | 0 | 5.29 | 59 |
| Thalamus | R | 6 | -24 | 9 | 5.53 | 10 |
| Cingulate | R | 9 | 30 | 30 | 6.28 | 36 |
| ControlParametric > PumpsParametric | ||||||
| Postcentral | L | -66 | -18 | 27 | 7.30 | 495 |
| Fusiform | R | 39 | -6 | -33 | 4.89 | 15 |
| Middle frontal gyrus | L | -21 | 18 | 48 | 4.45 | 107 |
| vmPFC | L | -12 | 33 | -15 | 5.51 | 58 |
| Correlationa | ||||||
| Negative correlation | ||||||
| Insula | R | 33 | 21 | 0 | -4.86 | 64 |
| Insula | L | -27 | 21 | -3 | -5.57 | 132 |
| Caudate | R | 9 | 6 | 9 | -5.22 | 65 |
| Caudate | L | -12 | 6 | 12 | -5.54 | 63 |
| Anterior cingulate | R | 6 | 39 | 9 | -3.88 | 45 |
| Positive correlation | ||||||
| Middle temporal gyrus | L | -45 | -60 | 3 | 7.59 | 293 |
| Middle temporal gyrus | R | 54 | 0 | -24 | 5.07 | 64 |
| Medial frontal gyrus | L | -18 | 39 | -12 | 5.15 | 111 |
| Culmen | R | 15 | -36 | -24 | 5.14 | 58 |
R, Right; L, Left; B, Bilateral. aCorrelation with mean number of adjusted pumps.