Table 3.
Significant clusters of activation in older adults.
| Region | L/R/B | X | Y | Z | t-value | Cluster size |
|---|---|---|---|---|---|---|
| Average | ||||||
| PumpsAverage > ControlAverage | ||||||
| Supplementary motor area, superior frontal gyrus, insula, caudate, putamen | B | -6 | 0 | 51 | 11.20 | 10387 |
| Lingual gyrus | B | 18 | -90 | -3 | 11.25 | 142 |
| Middle temporal gyrus | R | 57 | -27 | -12 | 3.99 | 24 |
| Inferior parietal lobule, Precuneus, Middle occipital gyrus | B | 48 | -45 | 51 | 7.42 | 976 |
| ControlAverage > PumpsAverage | ||||||
| Precuneus | B | -3 | -54 | 33 | 9.22 | 3330 |
| Middle temporal gyrus | L | -36 | 24 | -27 | 5.38 | 409 |
| Middle temporal gyrus | R | 60 | 6 | -15 | 8.32 | 201 |
| Superior temporal gyrus | R | 63 | -54 | 21 | 5.95 | 490 |
| Inferior frontal gyrus | L | -45 | 30 | -6 | 5.27 | 170 |
| vmPFC | B | -9 | 57 | 36 | 7.89 | 326 |
| Parametric | ||||||
| PumpsParametric > ControlParametric | ||||||
| Insula | R | 33 | 21 | -3 | 6.51 | 44 |
| Insula | L | -33 | 21 | -9 | 7.35 | 56 |
| Caudate | R | 15 | 6 | 3 | 5.08 | 13 |
| Supplementary motor area, cingulate | B | 6 | 18 | 51 | 6.28 | 30 |
| Lingual gyrus | B | -9 | -84 | -3 | 5.09 | 10 |
| ControlParametric > PumpsParametric | ||||||
| Inferior occipital gyrus | L | -42 | -69 | -6 | 6.14 | 93 |
| Lingual | R | 24 | -90 | -3 | 5.75 | 4 |
| Superior parietal lobule | L | -21 | -81 | 45 | 5.29 | 25 |
| Precentral gyrus | R | 51 | -12 | 54 | 4.61 | 7 |
R, Right; L, Left; B, Bilateral.