Table I.
Cases of Dup7 Identified When Screening Special Populations for Copy Number Variants
| Report | Population Screened | N | Dup7 cases |
|---|---|---|---|
| Depienne et al., 2007 | Autism spectrum disorder | 206 | 1 |
| Kirchhoff et al., 2007 | Intellectual disability | 258 | 1 |
| Torniero et al., 2008 | Epilepsy/neuronal migration defects | 134 | 2 |
| van der Aa et al., 2009 | Intellectual disability | 300 | 2 |
| Sanders et al., 2011 | Autism spectrum disorder | 1,124 | 4 |
| Malenfant et al., 2011 | Autism spectrum disorder | 1,142 | 1 |
| McGrew et al., 2012 | Autism spectrum disorder | 97 | 1 |
| Mulle et al., 2014 | Schizophrenia Cohort 1 Schizophrenia Cohort 2 (meta-analysis)a |
554 14,387 |
2 11b |
a
Samples analyzed only for Dup7.
b
Includes 9 cases of classic Dup7 and 2 cases in which the duplication extended at least 1 Mb beyond the classic telomeric breakpoint.