Figure 2. Transplantation of PO or PL microbiota does not change the body weight of mice.
(a) Scheme of experimental design is shown. Faecal samples were collected from 40 mice before switching to a high fat diet. Two microbiota donors were selected and their pre-high fat feeding faecal samples were transplanted to two groups of germfree mice. Microbiota recipients were challenged with a high fat diet for 10 weeks. (b) The criteria for selecting microbiota donors is based on 1st week and total body weight gain. Two donors, pre-lean (PL) and pre-obese (PO) and their weight gain performance in relation to the rest of mice are shown in a correlation graph. Comparison between donors and microbiota recipients in 1st week gain (c), final body weight (d) and feed efficiency (e) are shown. Unpaired t-tests were perform to compare PL-R and PO-R mice. Data are mean ± s.e.m., n = 12/group.