Table 2.

Frequency of mutations (n = patients)

Mutations detected in >20% of patients	Mutations detected in >15% of patients	Mutations detected in >10% of patients
TP53 (10), RB1 (6)	BCL6 (3), BLM (3), BRCA1 (3), CIC (3), MAP3K1 (3), NF1 (3), POT1 (3), WDR90 (3), WHSC1 (3)	APC (2), ARID2 (2), ASXL1 (2), ATRX (2), BRCA2 (2), CCT6B (2), CDK12 (2), CDKN2A (2), CHD2 (2), CHEK2 (2), CIITA (2), CPS1 (2), EP300 (2), EXOSC6 (2), FANCE (2), FRS2 (2), GRIN2A (2), HDAC7 (2), IRS2 (2), JAK1 (2), LRP1B (2), LRRK2 (2), MDM2 (2), MED12 (2), NOTCH1 (2), NTRK1 (2), PIK3R2 (2), RAD50 (2), SDHC (2), TET2 (2)