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Left column: Quantification of different collagen fiber metrics (count, alignment, length, straightness, and width) in images acquired from pancreatic cancer tissues using SHG and PSR-POL. Right column: Pearson correlation analysis between metrics generated by SHG and PSR-POL imaging. Data represent 92 patient tumors. Abbreviations: SHG, second harmonic generation; PSR-POL, picrosirius red stain with standard polarization microscopy.
