Table 1.
Computed physiological parameters of ATG5.
| Sr. no | Physiological parameters | Observations | ||
|---|---|---|---|---|
| 1. | Number of amino acids | 275 | ||
| 2. | Molecular weight | 32,447.2 Da | ||
| 3. | Theoretical pI | 5.47 | ||
| 4. | Total number of negatively charged residues (Asp + Glu) | 42 | ||
| 5. | Total number of positively charged residues (Arg + Lys) | 31 | ||
| 6. | Atomic composition: | |||
| Carbon C | 1480 | |||
| Hydrogen H | 2254 | |||
| Nitrogen N | 378 | |||
| Oxygen O | 418 | |||
| Sulfur S | 13 | |||
| 7. | Formula | C1480H2254N378O418S13 | ||
| 8. | Total number of atoms | 4543 | ||
| 9. | Estimated half-life | 30 h (mammalian reticulocytes, in vitro). >20 h (yeast, in vivo). >10 h (Escherichia coli, in vivo). |
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| 10. | The instability index (II) | 45.29 | ||
| 11. | Aliphatic index | 82.62 | ||
| 12. | Grand average of hydropathicity (GRAVY) | − 0.468 |