Table 4.
The non-synonymous Single Nucleotide Polymorphisms in the coding region of ATG5, two with putative damaging effects.
| SNP INFORMATION | SIFT | PolyPhen-2 | PredictSNP |
||||||
|---|---|---|---|---|---|---|---|---|---|
| PolyPhen-1 | nsSNPAnalyzer | PhD-SNP | MAPP | ||||||
| SNP ID |
Amino acid change | Score | Predicted impact | Probability score | Predicted impact | Prediction | Prediction | Prediction | Prediction |
| rs34793250 | M129 V | 1.00 | TOLERATED | 0.000 | BENIGN | Deleterious | Disease | Neutral | Deleterious |
| rs77859116 | I65V | 0.21 | TOLERATED | 0.000 | BENIGN | Neutral | Neutral | Neutral | Neutral |
| rs115576116 | A95D | 0.32 | TOLERATED | 0.000 | BENIGN | Neutral | Neutral | Deleterious | Neutral |