Table 6.

Frequencies of the target genotypes in different regions.

Population	CYP2C9 genotype frequencies(%)						No. of subjects	Reference
*1/*1	*1/*3	*3/*3	*1/*2	*2/*2	*2/*3
Han-Chinese	90.41	8.94	0.58	0.06	–	–	4928	Current review
Japanese	95.26	4.41	0.09	–	–	–	2277	Gaikwad et al. (2014)
Korean	90.82	9.10	0.08	–	–	–	1151	Gaikwad et al. (2014)
Indian	76.84	13.48	1.65	6.80	0.39	0.84	3510	Gaikwad et al. (2014)
Caucasian	66	12	0.5	19	1.4	1.3	1490	Wadelius et al. (2009); Daneshjou et al. (2013)
African	93.71	2.32	–	3.97	–	–	302	Daneshjou et al. (2013); Mushiroda et al. (2006)

Population	VKORC1 1173 genotype frequencies (%)			No. of subjects	Reference
TT	TC	CC
Han-Chinese	84.29	14.89	0.82	1712	Current review
Japanese	83.33	15.94	0.72	828	Mushiroda et al. (2006); Choi et al. (2011)
Korean	87.41	11.7	0.89	564	Choi et al. (2011); Kumar et al. (2013)
Indian	77.47	21.26	1.26	470	Kumar et al. (2013); Krajciova et al. (2014)
Caucasian	17.38	46.67	35.95	420	Krajciova et al. (2014); Limdi et al. (2008)
African	0.9	18.7	80.4	225	Limdi et al. (2008); Chin et al. (2013)
Population	VKORC1-1639 genotype frequencies (%)			No. of subjects	Reference
AA	GA	GG
Han-Chinese	79.87	17.77	2.36	2524	Current review
Japanese	83.21	16.06	0.72	800	Mushiroda et al. (2006); Choi et al. (2011)
Korean	86.91	13.09	–	298	Chin et al. (2013); Scott et al. (2008)
Indian	77.45	37.3	1.35	470	Kumar et al. (2013); Krajciova et al. (2014)
Caucasian	15	49	36	1461	Wadelius et al. (2009); Daneshjou et al. (2013)
African	2.0	17.7	80.3	300	Scott et al. (2008); Cha et al. (2010)
Puopulation	CYP4F2 genotype frequencies (%)			No. of subjects	Reference
CC	CT	TT
Han-Chinese	55.30	37.86	6.83	3100	Current review
Japanese	52.95	39.77	7.27	440	Cha et al. (2010); Wypasek et al. (2014)
Korean	41.69	46.65	11.66	403	Choi et al. (2011); Kumar et al. (2013)
Indian	33.5	49.4	17.1	445	Kumar et al. (2013); Krajciova et al. (2014)
Caucasian	7.31	41.75	50.94	479	Wypasek et al. (2014); Bress et al. (2012)
African	88.76	10.85	0.39	258	Bress et al. (2012); Ye et al. (2014)