Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Mar 3;19(8):pyw021. doi: 10.1093/ijnp/pyw021

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2016. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 3. — C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) had a differential effect on methamphetamine (METH)-induced microgliosis vs astrogliosis in the striatum. Although METH had a consistent effect on both micro- and astrogliosis, Hc-TeTx (Hc) had varied interactions with METH vis-a-vis these markers of central inflammatory responses. Photomicrographs of ionized calcium binding adaptor molecule 1 (Iba-1) (A) and glial fibrillary acidic protein antibody (GFAP)-stained (B) sections of the striatum of mice at 3 and 7 days after METH with and without Hc-TeTx (Hc) treatment. Histograms show the proportional stained area in the striatum. Data represent mean ± SEM, n = 6–8/group. *P<.05, **P<.01, ***P<.001 vs saline group, ###P<.001 vs METH group. Bar indicates 50 μm.